Endocrine Abstracts

Purpose: To analyze CT signs and parameters of vascularization of pulmonary neuroendocrine tumours (PNT) and their relationship with the development of ACTH ectopic syndrome.Materials and methods: 23 patients with PNT were evaluated with contrast-enhanced MDCT. Arterial and venous phases were obtained at 10 and 35 seconds after the attenuation of 200 HU at the descending aorta, a delayed phase was at 6–8 min after the start of injection of contrast...

Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare cause of Cushing syndrome and in 25–55% of cases is caused by mutations in ARMC5 gene. A 37 y.o. female was referred to our center with a diagnosis of ACTH-independent Cushing syndrome. Laboratory testing confirmed endogenous hypercortisolism (urinary free cortisol 5063.5 nmol/24 h (60–413), midnight salivary cortisol 56.6 nmol/l (0.5–9.4), midnight serum cortisol 1427 nmol/l (46–...

IntroductionClinically functioning gonadotroph adenomas (FGA) are rare, especially in men. We present a case of a LH/FSH-secreting functioning gonadotroph macroadenoma in an elderly patient, which manifested with visual impairment and was accompanied by secondary erythrocytosis.Clinical caseA 62-y.o. male was admitted to our hospital with a 9-month history of visual impairment and a 5-year history of plethora...